Poly's Glucosamine Enteric-Coated can be super absorbed by small intestine, it's a super natural joint supportive ingredients. Glucosamine is key constituents of larger compounds called glycosaminoglycans (GAGs) and glycoproteins (GPS), which allow cells in tissues to hold together. GAGs and GPS are necessary for the construction and maintenance of nearly all of the body's connective tissues and lubricating fluids: Bone matrix, cartilage, intestinal lining, joint fluid, ligaments, mucous membranes, skin and tendons. Glucosamine HCl is researched as good bioavailability as the Glucosamine Sulfate.